Introduction: Same active ingredient, completely different experience

THC is THC – or so you might think. But the difference between a smoked joint and an edible is enormous. With a joint, THC reaches the brain via the lungs in seconds. With edibles, it passes through the digestive tract, is metabolized in the liver – and thus unfolds a completely different, often much stronger effect. The same molecule, two completely different journeys in the body.

Route of absorption: Lungs vs. digestive system

Joint: The direct route to the bloodstream

When cannabis is smoked, THC is absorbed into the bloodstream almost immediately via the alveoli in the lungs. Within seconds, it reaches the brain – the effect is felt instantly. Therefore, smoking or vaping is well-suited for precisely controlling the effect. One more or one less puff directly alters the high.

However, some of the THC is destroyed during combustion. Only about 25–30% of the active ingredient actually reaches the bloodstream.

Edibles: The detour via the stomach

With edibles, the process takes significantly longer. The THC dissolves in the gastrointestinal tract, reaches the liver, and is converted there to 11-hydroxy-THC – a more potent variant. This form crosses the blood-brain barrier more easily and produces a deeper, more physical high. The effects typically begin after about 30–120 minutes .

Onset of effect & duration in comparison

This explains why many newcomers are surprised: If "nothing happens" after 45 minutes, more is often added – and then the double load comes at once.

The difference in chemical effect

When smoked, Δ9-THC becomes active directly and binds to CB1 receptors in the brain. In edibles, 11-hydroxy-THC is produced after conversion in the liver. This form more easily enters the brain, binds to receptors for a longer period, and is therefore more potent. A 10 mg edible can thus be more intense than a joint with a higher THC content.

Perceived effect: Head vs. Body

• Joint: Head-focused, fast, controllable – ideal for creative phases or short relaxation.
• Edible: Deeply physical, warm, lasting – perfect for evenings, sleep, or long-term relief.

Many medical users prefer edibles because the effect is more consistent and lasts longer – without the need for after-smoking.

Risks & Dosage

The most common mistake with edibles is incorrect dosage. With smoking, the high can be assessed immediately, but with edibles, the effects take so long to kick in that it's easy to consume too much.

Start low, go slow.

• Beginners: 2–5 mg THC per serving
• Experienced users: 10–20 mg THC
• Add more only after 2 hours – if necessary

CBD can help to mitigate the effects of excessively strong THC.

Health aspects

Smoke

• Affects airways & lungs
• Combustion products contain tar and carbon monoxide.
• Rapid onset of action, short duration

Edibles

• No smoke pollution – gentler
• Increased liver strain (metabolism of THC)
• The effect can be unpredictably strong.

Those who take preventative measures for their health or use cannabis medically often choose edibles or vaporizers.

Comparison summarized

Conclusion: Two paths – two worlds

Edibles and joints deliver the same active ingredient, but the way it's absorbed through the body determines its intensity and duration. Those seeking fast, controllable effects should opt for a joint or vaporizer. For a longer-lasting, physically noticeable effect, edibles are the better choice – provided the dosage is respectful.

Frequently Asked Questions (FAQ)